{"id":5936,"date":"2023-07-27T13:37:05","date_gmt":"2023-07-27T11:37:05","guid":{"rendered":"https:\/\/mycan.builtbygo.com\/?p=5936"},"modified":"2024-09-11T20:33:46","modified_gmt":"2024-09-11T18:33:46","slug":"thc-vs-cbd","status":"publish","type":"post","link":"https:\/\/br.mycannabisofficial.com\/pt\/blog\/thc-vs-cbd\/","title":{"rendered":"THC vs CBD: Compreender as diferen\u00e7as, os benef\u00edcios e as utiliza\u00e7\u00f5es"},"content":{"rendered":"

Os efeitos da can\u00e1bis medicinal dependem em grande medida dos canabin\u00f3ides THC (tetrahidrocanabinol) e CBD (canabidiol). (1) Neste artigo, ficar\u00e1 a saber quais s\u00e3o os dois canabin\u00f3ides mais famosos, quais os benef\u00edcios m\u00e9dicos que podem proporcionar e em que medida est\u00e3o regulamentados.<\/p>\n

THC vs. CBD: Qual \u00e9 a diferen\u00e7a?<\/h2>\n

O THC \u00e9 um composto qu\u00edmico que se encontra principalmente nas flores da planta feminina de can\u00e1bis. \u00c9 o componente psicoativo prim\u00e1rio respons\u00e1vel pelo efeito de euforia ou intoxica\u00e7\u00e3o do consumo de can\u00e1bis. O THC interage com o sistema endocanabin\u00f3ide do corpo humano para produzir uma s\u00e9rie de efeitos fisiol\u00f3gicos e psicol\u00f3gicos. (2) Os efeitos atribu\u00eddos incluem o relaxamento, a euforia (3), a altera\u00e7\u00e3o da perce\u00e7\u00e3o sensorial (4), o aumento do apetite e a redu\u00e7\u00e3o da dor (5).<\/p>\n

O CBD \u00e9 um canabin\u00f3ide que tamb\u00e9m se encontra nas plantas de can\u00e1bis. Ao contr\u00e1rio do THC, o interesse cient\u00edfico pelo CBD s\u00f3 surgiu ap\u00f3s a viragem do mil\u00e9nio. O CBD em si n\u00e3o tem efeitos psicoactivos, mas est\u00e1 associado a efeitos calmantes, analg\u00e9sicos e anti-inflamat\u00f3rios. (6) Este facto torna-o relevante para utiliza\u00e7\u00e3o terap\u00eautica. Uma vez que a legisla\u00e7\u00e3o sobre a cannabis medicinal se centra no THC, o estatuto exato de muitos produtos com CBD n\u00e3o \u00e9 claro. (7) O teor de THC e CBD \u00e9 geralmente especificado para os produtos de can\u00e1bis medicinal.<\/p>\n

CBD vs. THC: Vis\u00e3o geral<\/h3>\n\n\n\n\n<\/colgroup>\n\n\n\n\n\n\n\n
Carater\u00edstica<\/strong><\/span><\/td>\nTHC (Tetrahidrocanabinol)<\/strong><\/span><\/td>\nCBD (Cannabidiol)<\/strong><\/span><\/td>\n<\/tr>\n
\u00a0Psicoactividade<\/td>\nComposto psicoativo presente nas plantas de can\u00e1bis.<\/td>\nComposto n\u00e3o psicoativo presente nas plantas de can\u00e1bis.<\/td>\n<\/tr>\n
\u00a0Efeitos no corpo<\/td>\nProduz uma \"moca\" e altera a perce\u00e7\u00e3o.<\/td>\nN\u00e3o provoca uma \"moca\" e n\u00e3o altera a perce\u00e7\u00e3o.<\/td>\n<\/tr>\n
\u00a0Presta\u00e7\u00f5es m\u00e9dicas<\/td>\nPode ajudar a reduzir a dor, as n\u00e1useas e a aumentar o apetite.<\/td>\nPode ajudar a reduzir a dor, a inflama\u00e7\u00e3o, a ansiedade e as convuls\u00f5es.<\/td>\n<\/tr>\n
\u00a0Fonte<\/td>\nEncontrado em concentra\u00e7\u00f5es mais elevadas na marijuana.<\/td>\nEncontrado nas plantas de marijuana e de c\u00e2nhamo.<\/td>\n<\/tr>\n
\u00a0Investiga\u00e7\u00e3o<\/td>\nExtensivamente estudado, mas limitado por restri\u00e7\u00f5es legais.<\/td>\nInteresse crescente pela investiga\u00e7\u00e3o e popularidade crescente.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

THC vs. CBD: Efeitos psicoactivos<\/h2>\n

O THC \u00e9 uma subst\u00e2ncia psicoactiva que, dependendo da dosagem e do perfil exato do efeito da variedade de flor, pode induzir euforia, uma maior necessidade de falar, uma perce\u00e7\u00e3o alterada, maior criatividade e concentra\u00e7\u00e3o. Dependendo da toler\u00e2ncia individual, estes efeitos s\u00e3o percepcionados como uma experi\u00eancia intoxicante. No entanto, em conjunto com o CBD, h\u00e1 um maior efeito f\u00edsico, que indiretamente leva a um maior relaxamento, sonol\u00eancia e menos dor. (6) A intoxica\u00e7\u00e3o n\u00e3o ocorre.<\/p>\n

Pensa-se que o CBD e o THC interagem entre si. Assim, uma maior propor\u00e7\u00e3o de CBD num determinado produto de can\u00e1bis pode modular o efeito do THC contido, por exemplo, reduzindo a psicoactividade e a experi\u00eancia de intoxica\u00e7\u00e3o em favor dos benef\u00edcios terap\u00eauticos. A intera\u00e7\u00e3o entre o THC e o CBD \u00e9 objeto de investiga\u00e7\u00e3o em curso para adaptar as terapias com can\u00e1bis \u00e0s necessidades dos doentes (8).<\/p>\n

\"cannabis<\/p>\n

THC vs. CBD: Efeitos potenciais e aplica\u00e7\u00f5es m\u00e9dicas<\/h2>\n

N\u00e3o existe uma resposta geral sobre se o THC ou o CBD \u00e9 mais importante para uso m\u00e9dico. No entanto, a \u00eanfase \u00e9 colocada nos efeitos sin\u00e9rgicos das duas subst\u00e2ncias e tamb\u00e9m na sua intera\u00e7\u00e3o com os terpenos e outros componentes da can\u00e1bis, cujo peso varia consoante o cultivo. O termo efeito de comitiva \u00e9 frequentemente utilizado neste contexto para descrever o efeito individual de uma variedade de can\u00e1bis devido \u00e0 combina\u00e7\u00e3o espec\u00edfica de subst\u00e2ncias que cont\u00e9m. (9) Independentemente disso, os preparados de can\u00e1bis com diferentes propor\u00e7\u00f5es de THC e CBD desempenham diferentes pap\u00e9is na terapia com can\u00e1bis - adaptados ao quadro cl\u00ednico individual do paciente.<\/p>\n

1. Para a ansiedade<\/h3>\n

O CBD \u00e9 conhecido pelas suas potenciais propriedades ansiol\u00edticas (al\u00edvio da ansiedade). Pensa-se que interage com os receptores de serotonina no c\u00e9rebro, o que pode ajudar a regular o humor e a reduzir a ansiedade. Os doentes referem que o CBD pode criar uma sensa\u00e7\u00e3o de relaxamento e calma sem afetar as capacidades cognitivas.(10) Embora o THC tamb\u00e9m possa reduzir a ansiedade e ter um efeito estimulante do humor, tem o efeito oposto em doses elevadas ou em caso de intoler\u00e2ncia individual.(8)<\/p>\n

\"diferen\u00e7as<\/p>\n

2. Para perturba\u00e7\u00f5es do sono<\/h3>\n

Os efeitos potencialmente relaxantes do CBD podem facilitar o adormecimento e melhorar a qualidade do sono.(11) O THC, por outro lado, tem propriedades sedativas que reduzem o tempo necess\u00e1rio para adormecer, mas pode ter um impacto negativo no sono REM. Quando consumido frequentemente, pode provocar sonol\u00eancia diurna. (12)<\/p>\n

3. Para a dor<\/h3>\n

As prepara\u00e7\u00f5es ricas em THC s\u00e3o utilizadas, entre outras coisas, para aliviar a dor na esclerose m\u00faltipla e alguns tipos de dor neurop\u00e1tica, bem como em doentes com cancro.(13) O CBD, por outro lado, pode ter um efeito anti-inflamat\u00f3rio. Isto significa que \u00e9 utilizado no tratamento do reumatismo, da doen\u00e7a de Crohn e da colite ulcerosa. (14)<\/p>\n

4. Para as n\u00e1useas<\/h3>\n

O THC tem um efeito estimulante do apetite em muitas pessoas, raz\u00e3o pela qual \u00e9 utilizado para tratar dist\u00farbios alimentares. Al\u00e9m disso, entre outras coisas, pode ocorrer n\u00e1usea. produzido pela quimioterapia, reduzir. (4) Estes efeitos n\u00e3o foram demonstrados para o CBD.<\/p>\n

CBD vs. THC: Efeitos secund\u00e1rios<\/h2>\n

Devido \u00e0s suas propriedades psicoactivas, o THC tem efeitos secund\u00e1rios mais graves do que o CBD. Em doses elevadas, o consumo de THC pode provocar perturba\u00e7\u00f5es da mem\u00f3ria a curto prazo, problemas de coordena\u00e7\u00e3o e altera\u00e7\u00f5es da capacidade de discernimento. O THC tamb\u00e9m pode causar ansiedade, paranoia e aumento do ritmo card\u00edaco em algumas pessoas.<\/p>\n

No entanto, a orienta\u00e7\u00e3o m\u00e9dica durante a terapia com can\u00e1bis assegurar\u00e1 normalmente a dosagem adequada para evitar quaisquer efeitos secund\u00e1rios. Os efeitos secund\u00e1rios relatados do CBD incluem fadiga, boca seca e altera\u00e7\u00f5es no apetite ou no peso. No entanto, tanto o THC como o CBD s\u00e3o relativamente bem tolerados (13).<\/p>\n

\"utiliza\u00e7\u00f5es<\/p>\n

Refer\u00eancia:<\/h3>\n
    \n
  1. Elzinga, S., Raber, J., Fischerdick, J. T. (2015). Canabin\u00f3ides e terpenos como marcadores quimiotaxon\u00f4micos em Cannabis. Qu\u00edmica e Pesquisa de Produtos Naturais, 3(4).<\/li>\n
  2. https:\/\/doi.org\/10.4172\/2329-6836.1000181<\/a><\/li>\n
  3. Mouslech, Z., Valla, V. (2009). Sistema endocanabin\u00f3ide: Uma vis\u00e3o geral do seu potencial na pr\u00e1tica m\u00e9dica atual. PubMed, 30(2), 153-179.<\/li>\n
  4. https:\/\/pubmed.ncbi.nlm.nih.gov\/19675519\/#<\/a><\/li>\n
  5. Lee, J. (2023). Tetrahidrocanabinol e Recetor de Dopamina D1. ChemRxiv. Cambridge Open Engage.<\/li>\n
  6. https:\/\/doi.org\/10.26434\/chemrxiv-2023-d43gk<\/a><\/li>\n
  7. Mathew, R. J. et al. (1998). Atividade cerebelar e perturba\u00e7\u00e3o do sentido do tempo ap\u00f3s o THC. Brain Research, 797(2), 183-189.<\/li>\n
  8. https:\/\/doi.org\/10.1016\/S0006-8993<\/a>(98)00375-8<\/li>\n
  9. Kalant, H. (2001). Medicinal Use of Cannabis: History and Current Status (Utiliza\u00e7\u00e3o medicinal da can\u00e1bis: hist\u00f3ria e situa\u00e7\u00e3o atual). Pain Research and Management, vol. 6.<\/li>\n
  10. https:\/\/doi.org\/10.1155\/2001\/469629<\/a><\/li>\n
  11. Fine, P. G., & Rosenfeld, M. J. (2013). O sistema endocanabin\u00f3ide, canabin\u00f3ides e dor. Rambam Maimonides Medical Journal, 4(4), e0022.<\/li>\n
  12. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3820295\/<\/a><\/li>\n
  13. Wurglics, M. & Ude, C. (2020). Cannabis und Cannabinoide als legale Arzneimittel. Eine \u00dcbersicht aus pharmazeutischer Perspektive. Psychopharmakotherapie, 2020(27), 98-104.<\/li>\n
  14. https:\/\/www.ppt-online.de\/_Resources\/Persistent\/4\/f\/6\/e\/4f6e3fa792ef9e0949c9bc158ca71a25bc58f9d6\/ppt202003_artikel1573.pdf<\/a><\/li>\n
  15. Marco, E. M. et al. (2011). Sistema endocanabin\u00f3ide e psiquiatria: em busca de uma base neurobiol\u00f3gica para efeitos terap\u00eauticos prejudiciais e potenciais. Frontiers in Behavioral Neuroscience, 5.<\/li>\n
  16. https:\/\/doi.org\/10.3389\/fnbeh.2011.00063<\/a><\/li>\n
  17. Russo, EB. (2019). O caso do efeito Entourage e da cria\u00e7\u00e3o convencional de cannabis cl\u00ednica: Sem tens\u00e3o, sem ganho. Frente. Plant Sci, 9(1969).<\/li>\n
  18. https:\/\/doi.org\/10.3389\/fpls.2018.01969<\/a><\/li>\n
  19. Skelley, J. W. et al. (2020). Uso de canabidiol em ansiedade e transtornos relacionados \u00e0 ansiedade. Jornal da Associa\u00e7\u00e3o Americana de Farmac\u00eauticos, 60(1), 253-261.<\/li>\n
  20. https:\/\/doi.org\/10.1016\/j.japh.2019.11.008<\/a><\/li>\n
  21. Moltke, J. & Hondocha, C. (2021). Raz\u00f5es para o uso de canabidiol: um estudo transversal de usu\u00e1rios de CBD, com foco no estresse autopercebido, ansiedade e problemas de sono. Journal of Cannabis Research, 3(5).<\/li>\n
  22. https:\/\/doi.org\/10.1186\/s42238-021-00061-5<\/a><\/li>\n
  23. Schierenbeck, T. et al. (2008). Efeito das drogas il\u00edcitas recreativas no sono: Coca\u00edna, ecstasy e marijuana. Sleep Medicine Reviews, 12(5), 381-389.<\/li>\n
  24. https:\/\/doi.org\/10.1016\/j.smrv.2007.12.004<\/a><\/li>\n
  25. Johnson, J. R. et al. (2010). Estudo Multic\u00eantrico, Duplo-Blind-Randomizado, Controlado por Placebo, Grupo Paralelo da Efic\u00e1cia, Seguran\u00e7a e Tolerabilidade do THC: Extrato de CBD e Extrato de THC em Pacientes com Dor Intrat\u00e1vel Relacionada com o Cancro. Journal of Pain and Symptom Management, 39(2), 167-179.<\/li>\n
  26. https:\/\/doi.org\/10.1016\/j.jpainsymman.2009.06.008<\/a><\/li>\n
  27. Atalay, S. et al. (2020). Propriedades antioxidantes e anti-inflamat\u00f3rias do canabidiol. Antioxidantes, 9(1), 21.<\/li>\n
  28. https:\/\/doi.org\/10.3390\/antiox9010021<\/a><\/li>\n<\/ol>","protected":false},"excerpt":{"rendered":"

    Two of the best-known and best-studied cannabinoids are tetrahydrocannabinol (THC) and cannabidiol (CBD) - each with its own properties and effects on the human body. So let's get to know the differences between THC and CBD - from their benefits to their side effects.<\/p>","protected":false},"author":180,"featured_media":4308,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1559],"tags":[],"class_list":["post-5936","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medical-cannabis"],"yoast_head":"\nTHC vs. CBD: Understanding the Differences, Benefits, and Uses<\/title>\n<meta name=\"description\" content=\"Explore the key differences between THC and CBD, their unique effects, benefits, and uses in medicinal cannabis. Find out which may be right for you.\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"pt_PT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"THC vs. CBD: Understanding the Differences, Benefits, and Uses\" \/>\n<meta property=\"og:description\" content=\"Explore the key differences between THC and CBD, their unique effects, benefits, and uses in medicinal cannabis. 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